The first Captain America movie is probably the 2nd most forgotten of the 1st wave of MCU movies next to The Incredible Hulk, but on rewatch I think it holds up, and I think that's because like RDJ with Tony, Evans brings a certain likeability and charisma to the character that makes him just work for me.
It's not ultimately a great movie, but it's one that deserves appreciation.
With that said, let's begin:
"You are deluded Captain. You pretend to be a simple soldier but in reality you are just afraid to admit that we have left humanity behind!"
The Red Skull
Strength 6, Stamina 6, Agility 5, Dexterity 5, Fighting 5, Intellect 6, Awareness 5, Presence 5
Super Soldier Serum:
Immunity 4 [Aging, Intoxication, Disease, Poison; Limited to Half Effect], Speed 4 [64 km/h], Leaping 3 [16m], Regeneration 1 [1 every 9 rounds]
Armored Hydra coat
Hydra Energy Pistol (10 ep)
Benefit 2 [Head of Hydra], Daze 1 [Intimidation], Diehard, Languages 1 [Native German, English], Inspire 1, Quick Draw, Taunt, Equipment 3
Athletics 4 (+10), Close Combat: Unarmed 4 (+9), Deception 5 (+10), Expertise: Physics 6 (+12), Expertise: Teutonic Occultism 6 (+12), Expertise: Politics 4 (+10), Insight 6 (+11), Intimidation 7 (+12), Investigation 6 (+12), Perception 4 (+9), Persuasion (+5), Ranged Combat: Firearms 5 (+10), Stealth (+5), Technology 1 (+7), Vehicles 2 (+7)
Unarmed +9, Damage 6
Hydra Energy Pistol +10, Damage 8
Dodge 11, Parry 10
Toughness 8 (Protection 2), Fortitude 8, Will 8
Abilities 86 + Powers 10 + Advantages 11 + Skills 30 + Defenses 16 = Total 153
Arrogance: Red Skull is a megalomaniac and an egocentric believes himself to be the Umbermensch, beyond humanity
Enemies: Captain America, the SSR and the Allies in the 40's, and in the modern day, if they knew of his continued survival, pretty much every hero on Earth
The Red Skull is a villain who, by “virtue” of being a Nazi, essentially will never age out and always be relevant, unlike say those Yellow Peril and Red Scare characters that are pretty much relegated to the forgotten recesses of the Marvel Universe. The MCU take on him is more scientist than soldier, although his ruthlessness combined with his serum enhancements make him a brutal fighter, if an unskilled one (post Winter Soldier Cap would run circles around him in terms of combat prowess).
Speaking of the Erskine's Super Soldier Serum, the MCU version of it makes you explicitely superhuman, no mere “peak human ability” here, although some of the powers I give him here come Cap feats in later movies since in here Schmidt does actually very little fighting, appropriately enough for a mastermind-type of villain. Like many of the MCU villains he “dies” ambiguisly in his first movie, but has reappered in Infinity War as a sort of guardian for the Mind stone, and I've just now discovered that after Thanos claimed it he just moved on and is now active again in the MCU, unless he died again in the snap.
I was also tempted to make him buy Zola as minion, but decided against it.
Also credit where it's due, this build takes note from Thorpocalypse's own take on the more standard 616 Red Skull.